Oxytetracycline hydrochloride - MIB#35

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Revised December 2017

Approved Brands

  1. Terramycin - 50 contains oxytetracycline hydrochloride at 110 g/kg (Phibro Animal Health Corporation)
  2. Terramycin - 100 contains oxytetracycline hydrochloride at 220 g/kg (Phibro Animal Health Corporation)
  3. Terramycin - 200 contains oxytetracycline hydrochloride at 440 g/kg (Phibro Animal Health Corporation)
  4. Oxysol - 110 contains oxytetracycline hydrochloride at 110 g/kg (Bio Agri Mix LP)
  5. Oxysol 220 contains oxytetracycline hydrochloride at 220 g/kg (Bio Agri Mix LP)
  6. Oxysol 440 contains oxytetracycline hydrochloride at 440 g/kg (Bio Agri Mix LP)
  7. Oxytetracycline 50 Premix contains oxytetracycline hydrochloride at 110 g/kg (Bio Agri Mix LP)
  8. Oxytetracycline 100 Premix contains oxytetracycline hydrochloride at 220 g/kg (Bio Agri Mix LP)
  9. Oxytetracycline 200 Premix contains oxytetracycline hydrochloride at 440 g/kg (Bio Agri Mix LP)
  10. Oxy - 220 contains oxytetracycline hydrochloride at 220 g/kg (Bio Agri Mix LP)
  11. Oxy - 440 contains oxytetracycline hydrochloride at 440 g/kg (Bio Agri Mix LP)

Approved for use

In meal or pellet feed for broiler, replacement, and laying chickens; turkeys; lambs; swine; beef cattle; calves and calf milk replacers.

Approved claims

For broiler chickens - Claim 1, 2, 3, 4, 5, 6
For laying chickens - Claim 7, 8, 9, 10, 11
For replacement chickens - Claim 12, 13, 14, 15, 16, 17
For turkeys - Claim 18, 19, 20, 21, 22, 23, 24
For lambs - Claim 25, 26
For swine - Claim 27, 28, 29, 30, 31, 32, 33
For beef cattle - Claim 34
For calves - Claim 35
For calves (milk replacers) - Claim 36

Claim 1: As an aid in stimulating appetite, maintaining weight gains and feed effiiciency in broiler chickens during periods of stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for at least 5 days.

In the case of vaccination, feed for 8 - 10 days immediately following vaccination.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 2: As an aid in stimulating appetite and maintaining weight gains in broiler chickens when birds are expected to be exposed to mild attacks of Chronic Respiratory Disease (CRD) and/or Non-Specific Enteritis.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 3: As an aid in stimulating appetite and maintaining weight gains, and feed efficiency in broiler chickens in the presence of Chronic Respiratory Disease (CRD).

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 4: As an aid in stimulating appetite, maintaining weight gains, and feed efficiency in broiler chickens in the presence of Chronic Respiratory Disease (CRD) and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 5: As an aid in stimulating appetite and maintaining weight gains in broiler chickens in the presence of Non-Specific Enteritis.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 6: As an aid in increasing oxytetracycline levels in the blood of broiler chickens. The calcium level of this feed has been reduced to ...%.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration to broiler chickens.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Caution:

  • As an aid in increasing oxytetracycline levels in the blood, dietary calcium may be reduced to not less than 0.6%, and not more than 0.8%. Added calcium should be derived from calcium sulfate. Feed phosphorus levels should not be less than 0.55%.(Required on premix and supplement labels only.)
  • Do not feed to laying hens and turkeys.

Note:

  • Claim 6 is to be used in conjunction with another claim such as claim 4.

Claim 7: As an aid in stimulating appetite, maintaining weight gains, egg production, hatchability and feed efficiency in laying chickens during periods of stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for at least 5 days.

In the case of vaccination, feed for 8 - 10 days immediately following vaccination.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 8: As an aid in stimulating appetite and maintaining weight gains in laying chickens when birds are expected to be exposed to mild attacks of Chronic Respiratory Disease (CRD) and/or Non-Specific Enteritis.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 9: As an aid in stimulating appetite and maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in laying chickens in the presence of Chronic Respiratory Disease (CRD).

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 10: As an aid in stimulating appetite, and maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in laying chickens in the presence of Chronic Respiratory Disease (CRD) and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 11: As an aid in stimulating appetite and maintaining weight gains in laying chickens in the presence of Non-Specific Enteritis.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 12: As an aid in stimulating appetite, maintaining weight gains and feed efficiency in replacement chickens during periods of stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for at least 5 days.

In the case of vaccination, feed for 8 - 10 days immediately following vaccination.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 13: As an aid in stimulating appetite and maintaining weight gains in replacement chickens when birds are expected to be exposed to mild attacks of Chronic Respiratory Disease (CRD) and/or Non-Specific Enteritis.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 14: As an aid in stimulating appetite and maintaining weight gains, and feed efficiency in replacement chickens in the presence of Chronic Respiratory Disease (CRD).

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 15: As an aid in stimulating appetite, maintaining weight gains, and feed efficiency in replacement chickens in the presence of Chronic Respiratory Disease (CRD) and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 16: As an aid in stimulating appetite and maintaining weight gains in replacement chickens in the presence of Non-Specific Enteritis.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 17: As an aid in increasing oxytetracycline levels in the blood of replacement chickens. The calcium level of this feed has been reduced to ...%.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Caution:

  • As an aid in increasing oxytetracycline levels in the blood, dietary calcium may be reduced to not less than 0.6%, and not more than 0.8%. Added calcium should be derived from calcium sulfate. Feed phosphorus levels should not be less than 0.55%. (Required on premix and supplement labels only.)
  • Do not feed to laying hens and turkeys.

Note:

  • Claim 17 is to be used in conjunction with another claim such as claim 15.

Claim 18: As an aid in stimulating appetite and maintaining weight gains, egg production, hatchability and feed efficiency in turkeys during periods of stress caused by moving, debeaking, chilling, vaccination, and extreme temperature changes.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for at least 5 days.

In the case of vaccination, feed for 8 - 10 days immediately following vaccination.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 19: As an aid in stimulating appetite and maintaining weight gains in turkeys when birds are expected to be exposed to mild attacks of Chronic Respiratory Disease (CRD) and/or Non-Specific Enteritis.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Claim 20: As an aid in stimulating appetite, maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in turkeys in the presence of Chronic Respiratory Disease (CRD).

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 21: As an aid in stimulating appetite, maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in turkeys in the presence of Chronic Respiratory Disease (CRD) and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 22: As an aid in stimulating appetite and maintaining weight gains in turkeys in the presence of Non-Specific Enteritis.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 23: As an aid in the prevention of Synovitis and Infectious Sinusitis in turkeys.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 24: As an aid in the treatment of Synovitis in turkeys.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed as the sole ration when symptoms appear and continue until at least 2 weeks after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.

Claim 25: As an aid in the reduction of Bacterial Enteritis (Bacterial Diarrhoea) in creep-fed suckling lambs.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole creep feed during the suckling period.

Warning:

  • Discontinue the use of this medicated feed at least 4 days before treated lambs are slaughtered for use in food.

Claim 26: As an aid in the reduction of losses due to Enterotoxemia in feed-lot lambs.

Level of Drug:

22 mg/kg (0.0022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration while lambs are in the feed-lot.

Warning:

  • Discontinue the use of this medicated feed at least 4 days before treated lambs are slaughtered for use in food.

Claim 27: As an aid in prevention of Bacterial Enteritis(Bacterial Diarrhoea) in swine up to completion of 6 weeks of age.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed as the sole ration up to the completion of 6 weeks of age.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Claim 28: As an aid in prevention of Bacterial Enteritis (Bacterial Diarrhoea) in swine from 6 weeks of age up to 27-31 kg body weight.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed as the sole ration during the period of early growth from 6 weeks of age up to 27-31 kg.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Claim 29: As an aid in the treatment of Bacterial Enteritis (Bacterial Diarrhoea) in swine up to completion of 6 weeks of age.

Level of Drug:

220 mg/kg (0.022%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration up to completion of 6 weeks of age following the appearance of symptoms and until 3 days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Caution:

  • Pigs off feed should be given individual treatment.

Claim 30: As an aid in the treatment of Bacterial Enteritis (Bacterial Diarrhoea) in swine from 6 weeks of age up to 27-31 kg body weight.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration from 6 weeks of age up to 27-31 kg body weight following the appearance of symptoms and until 3 days after symptoms disappear.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Caution:

  • Pigs off feed should be given individual treatment.

Claim 31: As an aid in maintaining weight gains in the presence of Atrophic Rhinitis in swine.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration for as long as the symptoms of Atrophic Rhinitis persist.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Caution:

  • Do not use in Pre-starter feeds. (Required on premix and supplement labels only.)

Note:

  • This medicated feed has no effect on the organism causing Atrophic Rhinitis.

Claim 32: As an aid in stimulating appetite and maintaining weight gains during periods of stress caused by moving, vaccination, castration or extreme temperature changes in swine.

Level of Drug:

110 mg/kg (0.011%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration during periods of stress and until 10 days after the stress conditions have been eliminated.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughter for use in food.

Claim 33: As an aid in reducing the incidence of abortion in swine caused by Leptospirosis.

Level of Drug:

550 mg/kg (0.055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

When abortion in swine due to Leptospirosis has been diagnosed, feed this medicated feed at once as sole ration to pregnant and affected sows for a 2 week period.

Warning:

  • Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.

Note:

  • Good sanitation procedures must be practised to prevent spread of infection.

Claim 34: As an aid in reducing the incidence of Bloat in young cattle on pasture and in feedlots.

Level of Drug:

Level of the drug in the complete feed is to be such that each animal will receive 75 mg of oxytetracycline hydrochloride per head per day.

Directions:

Feed this medicated feed continuously.

Warning:

  • Discontinue the use of this medicated feed at least 5 days before treated animals are slaughtered for use in food.
  • Do not use in feeds for dairy cows.

Claim 35: As an aid in the prevention of Bacterial Enteritis (Bacterial Diarrhoea) in calves.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the complete feed.

Directions:

Feed this medicated feed continuously during period of early growth up to 136 kg of bodyweight.

Warning:

Discontinue the use of this medicated feed at least 5 days before treated calves are slaughtered for use in food.

Claim 36: As an aid in the prevention of Bacterial Enteritis (Bacterial Diarrhoea) in calves.

Level of Drug:

55 mg/kg (0.0055%) of oxytetracycline hydrochloride in the milk replacer powder.

Directions:

Feed this medicated feed continuously during periods of early growth up to 136 kg of bodyweight.

Warning:

Discontinue the use of this medicated feed at least 5 days before treated calves are slaughtered for use in food.

Accepted Compatibilities

Oxytetracycline hydrochloride is compatible with the following drug/drug combinations. For details refer to the MIB as indicated
MIB Medicated ingredientsFor use in feed for
27 Amprolium broiler chickens; replacement chickens; turkeys
7 Zoalene broiler chickens; replacement chickens; turkeys
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