Amprolium - MIB #27

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Revised October 2017

Approved Brands

  1. AMPROL FEED PREMIX contains amprolium 250 g/kg (Huvepharma Inc.)

Approved for use

In meal or pellet feed for turkeys, replacement chickens; broiler chickens; calves.

Approved claims

For turkeys - Claim 1
For replacement chickens - Claim 2, 3, 4
For broiler chickens - Claim 5
For calves - Claim 6

Claim 1: As an aid in the prevention of coccidiosis in turkeys.

Level of Drug:

125 mg/kg (0.0125%) of amprolium in the complete feed.

Directions:

Feed this medicated feed as the sole ration from one day of age up to and including 16 weeks of age.

Warning:

  1. Do not feed to laying birds in production.

Caution:

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Claim 2: Heavy Exposure to coccidiosis: As an aid in the prevention of deaths from coccidiosis in replacement chickens intended as conventional floor managed layers.

Level of Drug:

  1. 125 mg/kg (0.0125%) of amprolium in the complete feed to chickens aged from 0 to 5 weeks.
  2. 125 to 80 mg/kg (0.0125% to 0.008%) of amprolium in the complete feed to chickens aged from 5 to 9 weeks.
  3. 80 mg/kg (0.008%) of amprolium in the complete feed to chickens aged from 9 to 14 weeks.

Directions:

Feed the appropriate level of amprolium in the medicated feed as sole ration up to 14 weeks of age as follows:
Age of Chickens (wks) Level of amprolium in the complete feed (mg/kg)
0-5 125
5-9 (125-80)
9-14 80

Warning:

  1. Do not feed to laying birds in production.

Caution:

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Claim 3: Light to Moderate Exposure to coccidiosis: As an aid in the prevention of deaths from light to moderate infection of coccidiosis in replacement chickens intended as conventional floor managed layers.

Level of Drug:

  1. 80 mg/kg (0.008%) of amprolium in the complete feed to chickens aged from 0 to 5 weeks.
  2. 80 to 60 mg/kg (0.008% to 0.006%) of amprolium in the complete feed to chickens aged from 5 to 9 weeks.
  3. 60 mg/kg (0.006%) of amprolium in the complete feed to chickens aged from 9 to 14 weeks.

Directions:

Feed the appropriate level of amprolium in the medicated feed as sole ration up to 14 weeks of age as follows:
Age of Chickens (wks) Level of amprolium in the complete feed (mg/kg)
0-5 80
5-9 (80-60)
9-14 60

Warning:

  1. Do not feed to laying birds in production.

Caution:

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Claim 4: As an aid in prevention of deaths from coccidiosis in replacement chickens intended as caged layers.

Level of Drug:

125 or 250 mg/kg (0.0125% or 0.025%) of amprolium in the complete feed.

Directions:

Feed this medicated feed from one day of age until birds are placed in cages.

Warning:

  1. Do not feed to laying birds in production.

Caution:

  1. Do not use amprolium medicated feeds as a treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Claim 5: As an aid in prevention of deaths from coccidiosis in broiler chickens.

Level of Drug:

125 or 250 mg/kg (0.0125% or 0.025%) of amprolium in the complete feed.

Directions:

Feed this medicated feed as the sole ration.

Warning:

  1. Do not feed to laying birds in production.

Caution:

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Claim 6: As an aid in the prevention and treatment of coccidiosis caused by Eimeria bovis and Eimeria zuernii in calves.

Level of Drug:

500 mg/kg (0.05%) of amprolium in the complete feed.

Directions:

For prevention: Distribute this medicated feed so that each animal is supplied with 5 mg of amprolium per kg of body weight per day for 21 days during periods of exposure or when experience indicates that coccidiosis is likely to be a hazard (see Table 1 below).

For treatment: Distribute this medicated feed so that each animal is supplied with 10 mg of amprolium per kg of body weight per day for 5 days (see Table 2 below).

The tables below gives directions for using the 500 mg/kg medicated feed.

Table 1: 21-day Preventive Program
Animal Weight (kg) Amount of Amprolium (mg/head/day) Daily Intake of Medicated Feed (kg/head/day)
100 500 1
200 1000 2
300 1500 3
Table 2: 5-day Treatment Program
Animal Weight (kg) Amount of Amprolium (mg/head/day) Daily Intake of Medicated Feed (kg/head/day)
100 1000 2
200 2000 4
300 3000 6

Warning:

  1. Treated animals must not be slaughtered for use in food for at least 7 days after the latest treatment with this drug.

Caution:

  1. For a satisfactory diagnosis, a microscopic fecal examination should be done by a veterinarian or a diagnostic laboratory before treatment. When treating out breaks, the drug should be administered promptly after diagnosis.
  2. Do not feed this medicated feed to calves intended for future breeding.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid (Premix and Supplement labels only).

Accepted Compatibilities

Amprolium is compatible with the following drug/drug combinations. For details refer to the MIB as indicated.

Medicated ingredients For use in feed for
Chlortetracycline hydrochloride (MIB #10.1) broiler chickens; replacement chickens; turkeys
Zinc or methylene disalicylate bacitracin (MIB #10.2) broiler chickens; replacement chickens; turkeys
Penicillin from procaine penicillin (MIB #10.7) broiler chickens; replacement chickens; turkeys
Chlortetracycline hydrochloride (MIB #34) broiler chickens; replacement chickens; turkeys
Oxytetracycline hydrochloride (MIB #35) broiler chickens; replacement chickens; turkeys
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